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>Introduction -  SCOPE Workshop

 

>SCOPE Workshop — Key Questions for Each Session

 

>Program for SCOPE Workshop on SCI Functional Outcomes

 

>SCOPE Workshop Evaluation Form (Please return)

 

 

Session 1 — Natural History SCI

 

>Clinical Practice Guidelines—Outcomes Following Traumatic SCI

>SCI Clinical Trial Guidelines—Spontaneous Recovery

 

Additional Readings: >The Reliability of the Early SCI Examination

                              >Predicting Neurorecovery After SCI

                              >Late Neurorecovery After SCI

                              >Measurements and Recovery Patterns in  Multicenter Study

                              >Prognostic Value of Pinprick Preservation in AIS B Patients

 

Session 2 — Preclinical SCI Translation

 

>Preclinical References and Discussion Questions

>Preclinical Outline and Model Figures

 

Additonal Readings:  >Good Laboratory Practice in Stroke Research - Example For SCI

                              >Translating Basic Research Into New SCI Therapies - Kleitman

 

 

Session 3 — SCI Outcome Tools

 

>SCI Outcome Tools — Goals and Questions for Discussion

>SCI Clinical Trial Guidelines — Outcome Measures

 

Additional Readings: >Towards Guidelines for Evaluation of Measures

                              >Neuroimaging After SCI

                              >Pain After SCI

 

 

Session 4 — SCI Clinical Endpoints

 

>Issues for Discussion on Clinical Endpoints

>Patient-Reported Outcome Measures: Guidance for Industry

>Smallest Difference - Link Between Reproducibility and Responsiveness  - Beckerman

>Looking for Important Differences in Studies of Responsiveness - Beaton et al.

>Minimum Important Differences - Methods for Clinical Significance -  Guyatt et al.

 

 

Session 5 -  Adverse Events

 

>International Spinal Cord Injury Core Data Set

>International Spinal Cord Injury Data Sets

>SCI Data Sets Symposium - October 25, 2008

 

Additional Readings:  >Urodynamic Basic SCI Data Set

                               >SCI Pain Basic Data Set

                               >Lower Urinary Tract Function Basic SCI Data Set

                               >Bowel Function Basic SCI Data Set

                               >Bowel Function Extended SCI Data Set

 

Session 6 -  Confounding Factors

 

>Confounding Factors Discussion Questions

>SCI Clinical Trial Guidelines - Inclusion/Exclusion Criteria and Ethics

>Constraint-Induced Movement Therapy and SCI

>Motor-Training

>Neuronal Stimulation in Central Nervous System Plasticity and Neurorehab Strategies

>Neuroplasticity After Spinal Cord Injury

 

Additional Readings: >Diff. Effect of SCI and Functional Impairment on Brain Activation

                              >Neurotrophic Factors Promote Locomotor Recovery

                              >Plasticity of the Spinal Neural Circuitry After Injury

                              >Adaptation in the Motor Cortex Following SCI

                              >How Does the Human Brain Deal With a Spinal Cord Injury

                              >Functional Recovery After Exposure to an Enriched Environment

                              >Enriched Environment  and Astrocytes in CNS Regeneration

SCOPE Workshop—November 14, 2008

Spinal Cord Outcomes Partnership Endeavor